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There are a number of laboratories at APL that are central to the work of its Precision Strike organization. Most reside in the Force Projection Department and are managed by Precision Strike technical groups, but Precision Strike programs can also reach out, as required, to use facilities nominally owned and operated by other APL departments.

Image Simulation (ISIM) Laboratory

ISIM LabThe Weapon and Targeting Systems Group operates the ISIM Laboratory. This laboratory's primary capability is to produce several varieties of computer-generated, synthetic-image data. In addition, the ISIM Laboratory can analyze both synthetic and real image data. The kinds of image data include optical, infrared, synthetic aperture radar (SAR), interferometric SAR, laser radar, and digital topography. The laboratory contains a number of workstations and servers linked by network connections. In addition, the main laboratory has the capability to generate video animation.

Air Vehicle Systems Engineering Laboratory (AVSEL)

AMSLThe AVSEL is a secure, multi-purpose, systems analysis facility operated by the Aerospace Systems Design and Electronic Warfare Systems Groups. The AVSEL provides an environment to conduct systems engineering, architecting, and analysis to support development and operational employment of joint service aircraft and weapons, with emphasis on interconnectivity, interoperability, and total system effectiveness. Additionally, this same environment enables engineers and analysts to access and optimize electronic attack operations and tactics to ensure the survivability of aircraft and weapons systems by developing advanced technology concepts for air defense suppression.

Mission Planning Development Laboratory (MPDL)

MPDLThe MPDL is a computer processing facility that is operated by the Weapon and Targeting Systems Group. MPDL performs a variety of tasks associated primarily with development and validation of image data products used for cruise missile mission planning. Historically, these tasks have focused on making improvements to Digital Scene Matching Area Correlator (DSMAC) navigation. More recently, the emphasis has been on targeting data improvements and developing the technology behind precision terrain-aided navigation (PTAN). The laboratory has also been used for dynamic missile simulations.

Controls Systems Integration Facility (CSIF)

The Command and Control Group operates the CSIF. The CSIF provides an environment for the development of new concepts that will enhance the collective responsiveness of power projection systems. The facility offers an extensive set of resources that includes computers, network communications, and display devices. These resources can be used to model advanced concepts and planned improvements for combat system elements, to develop distributed simulations for exercising those elements, and to design advanced human–computer interfaces. The CSIF provides spaces for assembling equipment into operationally representative demonstrations that are augmented by group view displays and briefing areas for conveying key points to an audience. Network connectivity to other APL facilities and external organizations allows collaborative ventures.

DDG1000 System Integration Laboratory

Also operated by the Command and Control Group, the DDG1000 System Integration Laboratory houses APL's suite of systems to measure the mission effectiveness of various DDG1000 subsystems. At its core, the facility hosts a central meeting and computer/display integrated development environment, enabling collaborative access between APL and other DDG1000 development participants. As the DDG1000 moves into production, APL will progressively host design agent and independently developed system and subsystem models to perform detailed mission effectiveness assessments as the DDG1000 detail design progresses.